Contact lens product

ABSTRACT

A contact lens product includes a multifocal contact lens and a buffer solution. The multifocal contact lens includes a central region and at least one annular region. The annular region concentrically surrounds the central region. A diopter of the annular region is different from a diopter of the central region. The multifocal contact lens is immersed in the buffer solution, and the buffer solution includes a cycloplegic agent.

RELATED APPLICATIONS

This application claims priority to Taiwan Application Serial Number104130460, filed Sep. 15, 2015, and Taiwan Application Serial Number104135628, filed Oct. 29, 2015, which are incorporated by referenceherein in its entirety.

BACKGROUND

Technical Field

The present disclosure relates to a contact lens product. Moreparticularly, the present disclosure relates to a contact lens productwhich can prevent myopia or control a progression of myopia.

Description of Related Art

According to the data of World Health Organization (WHO), the prevalenceof myopia in all world countries is between 8% and 62%. However, surveysshow that the prevalence of myopia in teenagers and children under 18years old in Taiwan is up to 85%, which is significantly beyond othercountries. One reason is probably due to the highly developed 3Celectronic devices in recent years, which results in improper stimulusesand overuse of eyes of young children prematurely. Current researchesshow that once young children suffer early-onset myopia, the degree ofmyopia will increase with a certain speed. Current researches furthershow that the lower the age at which the myopia occurs is, the higherprobability of becoming high myopia (greater than or equal to 6.0 D)will be. A person suffering high myopia is more likely to further sufferserious complications, such as retinal detachment and glaucoma.Therefore, if a controlling or moderating method can be conducted whenthe pseudomyopia is observed in the young children, the pseudomyopia canbe effectively prevented from becoming myopia, and the high myopia canbe further prevented.

The main cause of myopia is a variation of the optical structure ofeyeballs. The optical image is mainly affected by the factors, such ascornea, lens and the length of the eyeballs. As for a normal person,lights can be precisely focused on the retina thereof so as to obtain aclearly image. However, as for a person suffering myopia, lights arefocused in front of the retina thereof due to an excessive diopter(refractive myopia) or an excessive axial length of the eyeball (axialmyopia), so that a blurred image is obtained. Symptoms of myopia ofyoung children can be divided into myopia and pseudomyopia, wherein themyopia occurs due to an excessive axial length of the eyeball and cannotbe corrected. However, the pseudomyopia is a temporary symptom caused byexcessive tension of ciliary muscle and can be corrected. Clinically,there are many methods for correcting children pseudomyopia. The mainmethods include wearing orthokeratology and applying long-actingmydriatics. However, the orthokeratology may result in a highly externalpressure which makes the wearer uncomfortable. When applying thelong-acting mydriatics alone, a higher concentration dose is usuallyrequired. Accordingly, the probability of drug side effects is enhanced,too.

SUMMARY

According to one aspect of the present disclosure, a contact lensproduct includes a multifocal contact lens and a buffer solution. Themultifocal contact lens is immersed in the buffer solution. Themultifocal contact lens includes a central region and at least oneannular region. The annular region concentrically surrounds the centralregion, wherein a diopter of the annular region is different from adiopter of the central region. The buffer solution includes acycloplegic agent. When a weight percentage concentration of thecycloplegic agent in the buffer solution is ConA, the followingcondition is satisfied:0<ConA≤1%.

According to another aspect of the present disclosure, a contact lensproduct includes a multifocal contact lens. A composition formanufacturing the multifocal contact lens includes a blue-light blockingagent.

BRIEF DESCRIPTION OF THE DRAWINGS

The present disclosure can be more fully understood by reading thefollowing detailed description of the embodiment, with reference made tothe accompanying drawings as follows:

FIG. 1 is a schematic view of a contact lens product according to oneembodiment of the present disclosure;

FIG. 2 is a schematic plan view of a multifocal contact lens in FIG. 1;

FIG. 3 is a schematic plan view of a multifocal contact lens accordingto another embodiment of the present disclosure;

FIG. 4 is a schematic plan view of a multifocal contact lens accordingto yet another embodiment of the present disclosure;

FIG. 5 shows a relationship between a radius and a diopter of amultifocal contact lens of the 1st example;

FIG. 6 shows a relationship between a radius and a diopter of amultifocal contact lens of the 2nd example;

FIG. 7 shows a relationship between a wavelength and a transmittance ofthe multifocal contact lens of the 2nd example and a multifocal contactlens of the 1st comparative example;

FIG. 8 shows a relationship between a radius and a diopter of amultifocal contact lens of the 3rd example;

FIG. 9 shows a relationship between a radius and a diopter of amultifocal contact lens of the 4th example;

FIG. 10 shows a relationship between a wavelength and a transmittance ofthe multifocal contact lens of the 4th example and a multifocal contactlens of the 2nd comparative example;

FIG. 11 shows a relationship between a radius and a diopter of amultifocal contact lens of the 5th example;

FIG. 12 shows a relationship between a radius and a diopter of amultifocal contact lens of the 6th example;

FIG. 13 shows a relationship between a radius and a diopter of amultifocal contact lens of the 7th example;

FIG. 14 shows a relationship between a wavelength and a transmittance ofthe multifocal contact lens of the 7th example and a multifocal contactlens of the 3rd comparative example;

FIG. 15 shows a relationship between a radius and a diopter of amultifocal contact lens of the 8th example;

FIG. 16 shows a relationship between a radius and a diopter of amultifocal contact lens of the 9th example;

FIG. 17 shows a relationship between a radius and a diopter of amultifocal contact lens of the 10th example;

FIG. 18 shows a relationship between a radius and a diopter of amultifocal contact lens of the 11th example;

FIG. 19 shows a relationship between a wavelength and a transmittance ofthe multifocal contact lens of the 11th example and a multifocal contactlens of the 4th comparative example;

FIG. 20 shows a relationship between a radius and a diopter of amultifocal contact lens of the 12th example; and

FIG. 21 shows a relationship between a wavelength and a transmittance ofthe multifocal contact lens of the 12th example and a multifocal contactlens of the 5th comparative example.

DETAILED DESCRIPTION

FIG. 1 is a schematic view of a contact lens product 100 according toone embodiment of the present disclosure. The contact lens product 100includes a multifocal contact lens 110 and a buffer solution 120. Themultifocal contact lens 110 is immersed in the buffer solution 120.

FIG. 2 is a schematic plan view of the multifocal contact lens 110 inFIG. 1. The multifocal contact lens 110 includes a central region 111and a first annular region 112. The first annular region 112concentrically surrounds the central region 111. A diopter of the firstannular region 112 is different from a diopter of the central region111. Therefore, the multifocal contact lens 110 is featured withmulti-focus function, the peripheral image can be formed in front of theretina, which can moderate the increase of the axial length of theeyeball, and the exacerbation of myopia can be prevented. According toone example of the present disclosure, the diopter of the central region111 is fixed.

At least one of the central region 111 and the first annular region 112of the multifocal contact lens 110 is aspheric. Therefore, it isfavorable to design the first annular region 112 with a gradientdiopter.

Referring back to FIG. 1, the buffer solution 120 includes a cycloplegicagent. When a weight percentage concentration of the cycloplegic agentin the buffer solution 120 is ConA, the following condition issatisfied: 0<ConA≤1%. Therefore, the concentration of the cycloplegicagent is proper, which is favorable to relax the ciliary muscle andreduce the probability of drug side effects. Alternatively, thefollowing condition can be satisfied: 0<ConA≤0.5%. Alternatively, thefollowing condition can be satisfied: 0<ConA≤0.25%. Alternatively, thefollowing condition can be satisfied: 0<ConA≤0.1%. Alternatively, thefollowing condition can be satisfied: 0<ConA≤0.05%. Alternatively, thefollowing condition can be satisfied: 0<ConA≤0.01%. The buffer solution120 can be prepared by providing a basic solution, wherein the basicsolution can be a commercially available solution for immersing andpreserving contact lenses. Then the cycloplegic agent is added into thebasic solution to a required concentration, wherein chemical reactionsdo not occur between the basic solution and the cycloplegic agent.

According to the aforementioned contact lens product 100, a compositionfor manufacturing the multifocal contact lens 110 can include ablue-light blocking agent. Therefore, the multifocal contact lens 110can block high-energy blue lights, and the probability that the retinahurt by the blue lights can be reduced. According to one example of thepresent disclosure, the blue-light blocking agent can be4-(phenyldiazenyl) phenyl methacrylate.

According to the aforementioned contact lens product 100, thecomposition for manufacturing the multifocal contact lens 110 caninclude a UV (Ultraviolet) blocking agent. The UV blocking agent can bebut is limited to 2-[3-(2H-benzotriazol-2-yl)-4-hydroxyphenyl]ethylmethacrylate, 4-methacryloxy-2-hydroxybenzophenone, 2-phenylethylacrylate, 2-phenylethyl methacrylate,2-(2′-hydroxy-5′-methacryloxyethylphenyl)-2H-benzotriazole or2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate. Therefore, the multifocalcontact lens 110 can block high-energy UV lights, and the probabilitythat the retina hurt by the UV lights can be reduced. According to oneexample of the present disclosure, the UV blocking agent can be2-(2′-hydroxy-5′-methacryloxyethylphenyl)-2H-benzotriazole. According toanother example of the present disclosure, the UV blocking agent can be2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate. The aforementioned UVblocking agents can be used simultaneously or separately.

According to the aforementioned contact lens product 100, the multifocalcontact lens 110 can be made of silicone hydrogel. Therefore, the oxygenpermeability of the multifocal contact lens 110 can be enhanced, and thephenomena, such as red eyes, bloodshot eyes and swell, caused by thehypoxia of cornea can be prevented. Accordingly, the long wear comfortcan be provided. The silicone hydrogel can be but is not limited to thecontact lens material classified as Group V by U.S. FDA (U.S. Food andDrug Administration), such as Balafilcon A, Comfilcon A, Efrofilcon A,Enfilcon A, Galyfilcon A, Lotrafilcon A, Lotrafilcon B, Narafilcon A,Narafilcon B, Senofilcon A, Delefilcon A and Somofilcon A.

The composition for manufacturing the silicone hydrogel can include2-hydroxyethyl methacrylate,3-methacryloyloxypropyltris(trimethylsilyloxy)silane,2-hydroxy-2-methyl-propiophenone, N-vinyl-2-pyrrolidinone, N, N-dimethylacrylamide, ethylene glycol dimethacrylate,3-(3-methacryloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methylsilane,isopropyl alcohol and methacrylic acid.

Preferably, a weight percentage concentration of the ingredients of thecomposition for manufacturing the silicone hydrogel can be as follows.The weight percentage concentration of the 2-hydroxyethyl methacrylateis 0.05% to 25%, the weight percentage concentration of the3-methacryloyloxypropyltris(trimethylsilyloxy)silane is 0.1% to 40%, theweight percentage concentration of the 2-hydroxy-2-methyl-propiophenoneis 0.01% to 5%, the weight percentage concentration of theN-vinyl-2-pyrrolidinone is 0.1% to 35%, the weight percentageconcentration of the N,N-dimethyl acrylamide is 0.1% to 40%, the weightpercentage concentration of the ethylene glycol dimethacrylate is 0.01%to 5%, the weight percentage concentration of the3-(3-methacryloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methylsilaneis 0.1% to 30%, the weight percentage concentration of the isopropylalcohol is 0.1% to 30%, and the weight percentage concentration of themethacrylic acid is 0.01% to 5%.

More preferably, the weight percentage concentration of the ingredientsof the composition for manufacturing the silicone hydrogel can be asfollows. The weight percentage concentration of the 2-hydroxyethylmethacrylate is 0.1% to 10%, the weight percentage concentration of the3-methacryloyloxypropyltris(trimethylsilyloxy)silane is 1% to 40%, theweight percentage concentration of the 2-hydroxy-2-methyl-propiophenoneis 0.1% to 2%, the weight percentage concentration of theN-vinyl-2-pyrrolidinone is 1% to 35%, the weight percentageconcentration of the N,N-dimethyl acrylamide is 1% to 20%, the weightpercentage concentration of the ethylene glycol dimethacrylate is 0.1%to 2%, the weight percentage concentration of the3-(3-methacryloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methylsilaneis 1% to 30%, the weight percentage concentration of the isopropylalcohol is 1% to 20%, and the weight percentage concentration of themethacrylic acid is 0.1% to 2%.

The composition for manufacturing the silicone hydrogel can include2-hydroxyethyl methacrylate,3-methacryloyloxypropyltris(trimethylsilyloxy)silane,2-hydroxy-2-methyl-propiophenone, N-vinyl-2-pyrrolidinone, N,N-dimethylacrylamide, ethylene glycol dimethacrylate,(3-acryloxy-2-hydroxypropoxypropyl)terminated polydimethylsiloxane and1-hexanol.

Preferably, a weight percentage concentration of the ingredients of thecomposition for manufacturing the silicone hydrogel can be as follows.The weight percentage concentration of the 2-hydroxyethyl methacrylateis 0.05% to 25%, the weight percentage concentration of the3-methacryloyloxypropyltris(trimethylsilyloxy)silane is 0.1% to 40%, theweight percentage concentration of the 2-hydroxy-2-methyl-propiophenoneis 0.01% to 5%, the weight percentage concentration of theN-vinyl-2-pyrrolidinone is 0.1% to 35%, the weight percentageconcentration of the N,N-dimethyl acrylamide is 0.1% to 40%, the weightpercentage concentration of the ethylene glycol dimethacrylate is 0.01%to 5%, the weight percentage concentration of the(3-acryloxy-2-hydroxypropoxypropyl)terminated polydimethylsiloxane is0.1% to 40%, and the weight percentage concentration of the 1-hexanol is0.1% to 30%.

More preferably, the weight percentage concentration of the ingredientsof the composition for manufacturing the silicone hydrogel can be asfollows. The weight percentage concentration of the 2-hydroxyethylmethacrylate is 0.1% to 10%, the weight percentage concentration of the3-methacryloyloxypropyltris(trimethylsilyloxy)silane is 1% to 40%, theweight percentage concentration of the 2-hydroxy-2-methyl-propiophenoneis 0.1% to 2%, the weight percentage concentration of theN-vinyl-2-pyrrolidinone is 1% to 35%, the weight percentageconcentration of the N,N-dimethyl acrylamide is 1% to 20%, the weightpercentage concentration of the ethylene glycol dimethacrylate is 0.1%to 2%, the weight percentage concentration of the(3-acryloxy-2-hydroxypropoxypropyl)terminated polydimethylsiloxane is 1%to 40%, and the weight percentage concentration of the 1-hexanol is 1%to 30%.

The composition for manufacturing the silicone hydrogel can include2-hydroxyethyl methacrylate,3-methacryloyloxypropyltris(trimethylsilyloxy)silane,2-hydroxy-2-methyl-propiophenone, N-vinyl-2-pyrrolidinone, N,N-dimethylacrylamide, polysiloxane macromer, methyl methacrylate and ethanol.

Preferably, a weight percentage concentration of the ingredients of thecomposition for manufacturing the silicone hydrogel can be as follows.The weight percentage concentration of the 2-hydroxyethyl methacrylateis 0.05% to 25%, the weight percentage concentration of the3-methacryloyloxypropyltris(trimethylsilyloxy)silane is 0.1% to 40%, theweight percentage concentration of the 2-hydroxy-2-methyl-propiophenoneis 0.01% to 5%, the weight percentage concentration of theN-vinyl-2-pyrrolidinone is 0.1% to 35%, the weight percentageconcentration of the N,N-dimethyl acrylamide is 0.1% to 40%, the weightpercentage concentration of the polysiloxane macromer is 0.1% to 40%,the weight percentage concentration of the methyl methacrylate is 0.1%to 20%, and the weight percentage concentration of the ethanol is 0.1%to 30%.

More preferably, the weight percentage concentration of the ingredientsof the composition for manufacturing the silicone hydrogel can be asfollows. The weight percentage concentration of the 2-hydroxyethylmethacrylate is 0.1% to 10%, the weight percentage concentration of the3-methacryloyloxypropyltris(trimethylsilyloxy)silane is 1% to 40%, theweight percentage concentration of the 2-hydroxy-2-methyl-propiophenoneis 0.1% to 2%, the weight percentage concentration of theN-vinyl-2-pyrrolidinone is 1% to 35%, the weight percentageconcentration of the N,N-dimethyl acrylamide is 1% to 20%, the weightpercentage concentration of the polysiloxane macromer is 1% to 40%, theweight percentage concentration of the methyl methacrylate is 1% to 10%,and the weight percentage concentration of the ethanol is 1% to 20%.

According to one example of the present disclosure, the composition formanufacturing the silicone hydrogel can further include a blue-lightblocking agent or a UV blocking agent. Preferably, the weight percentageconcentration of the blue-light blocking agent or the UV blocking agentof the composition for manufacturing the silicone hydrogel is 0.01% to10%. More preferably, the weight percentage concentration of theblue-light blocking agent or the UV blocking agent for manufacturing thecomposition of the silicone hydrogel is 0.1% to 5%.

By adjusting the ratio of the ingredients of the composition formanufacturing the silicone hydrogel, an oxygen permeability and ahardness of the multifocal contact lens 110 can be effectively enhanced.Furthermore, the composition for manufacturing the silicone hydrogel canselectively include other ingredients according to practical needs.

According to the aforementioned contact lens product 100, the multifocalcontact lens 110 can be made of hydrogel. Therefore, the moisture,smoothness and softness of the multifocal contact lens 110 can bemaintained, and is capable of long wear. Furthermore, the foreign bodysensation can be avoided when wearing the multifocal contact lens 110.The hydrogel can be but is not limited to the contact lens materialclassified as Group I by U.S. FDA, i.e., nonionic polymers having a lowmoisture content (less than 50 wt %), such as Helfilcon A&B, HioxifilconB, Mafilcon, Polymacon, Tefilcon and Tetrafilcon A. Alternatively, thehydrogel can be but is not limited to the contact lens materialclassified as Group II by U.S. FDA, i.e., nonionic polymers having ahigh moisture content (greater than 50 wt %), such as Acofilcon A,Alfafilcon A, Hilafilcon B, Hioxifilcon A, Hioxifilcon B, Hioxifilcon D,Nelfilcon A, Nesofilcon A, Omafilcon A and Samfilcon A. Alternatively,the hydrogel can be but is not limited to the contact lens materialclassified as Group III by U.S. FDA, i.e., ionic polymers having a lowmoisture content (less than 50 wt %), such as Deltafilcon A.Alternatively, the hydrogel can be but is not limited to the contactlens material classified as Group IV by U.S. FDA, i.e., ionic polymershaving a high moisture content (greater than 50 wt %), such as EtafilconA, Focofilcon A, Methafilcon A, Methafilcon B, Ocufilcon A, Ocufilcon B,Ocufilcon C, Ocufilcon D, Ocufilcon E, Phemfilcon A and Vifilcon A.

The composition for manufacturing the hydrogel can include2-hydroxyethyl methacrylate, ethylene glycol dimethacrylate,2-hydroxy-2-methyl-propiophenone, glycerol, 1,1,1-trimethylol propanetrimethacrylate and methacrylic acid.

Preferably, a weight percentage concentration of the ingredients of thecomposition for manufacturing the hydrogel can be as follows. The weightpercentage concentration of the 2-hydroxyethyl methacrylate is 10% to96%, the weight percentage concentration of the ethylene glycoldimethacrylate is 0.01% to 5%, the weight percentage concentration ofthe 2-hydroxy-2-methyl-propiophenone is 0.01% to 5%, the weightpercentage concentration of the glycerol is 0.1% to 30%, the weightpercentage concentration of the 1,1,1-trimethylol propanetrimethacrylate is 0.01% to 5%, and the weight percentage concentrationof the methacrylic acid is 0.01% to 5%.

More preferably, the weight percentage concentration of the ingredientsof the composition for manufacturing the hydrogel can be as follows. Theweight percentage concentration of the 2-hydroxyethyl methacrylate is40% to 96%, the weight percentage concentration of the ethylene glycoldimethacrylate is 0.1% to 2%, the weight percentage concentration of the2-hydroxy-2-methyl-propiophenone is 0.1% to 2%, the weight percentageconcentration of the glycerol is 0.1% to 20%, the weight percentageconcentration of the 1,1,1-trimethylol propane trimethacrylate is 0.1%to 2%, and the weight percentage concentration of the methacrylic acidis 0.1% to 2%.

The composition for manufacturing the hydrogel can include2-hydroxyethyl methacrylate, ethylene glycol dimethacrylate,2-hydroxy-2-methyl-propiophenone, glycerol, 1,1,1-trimethylol propanetrimethacrylate and glycerol monomethacrylate.

Preferably, a weight percentage concentration of the ingredients of thecomposition for manufacturing the hydrogel can be as follows. The weightpercentage concentration of the 2-hydroxyethyl methacrylate is 10% to94.87%, the weight percentage concentration of the ethylene glycoldimethacrylate is 0.01% to 5%, the weight percentage concentration ofthe 2-hydroxy-2-methyl-propiophenone is 0.01% to 5%, the weightpercentage concentration of the glycerol is 0.1% to 30%, the weightpercentage concentration of the 1,1,1-trimethylol propanetrimethacrylate is 0.01% to 5%, and the weight percentage concentrationof the glycerol monomethacrylate is 5% to 60%.

More preferably, the weight percentage concentration of the ingredientsof the composition for manufacturing the hydrogel can be as follows. Theweight percentage concentration of the 2-hydroxyethyl methacrylate is40% to 79.6%, the weight percentage concentration of the ethylene glycoldimethacrylate is 0.1% to 2%, the weight percentage concentration of the2-hydroxy-2-methyl-propiophenone is 0.1% to 2%, the weight percentageconcentration of the glycerol is 0.1% to 20%, the weight percentageconcentration of the 1,1,1-trimethylol propane trimethacrylate is 0.1%to 2%, and the weight percentage concentration of the glycerolmonomethacrylate is 20% to 50%.

The composition for manufacturing the hydrogel can include2-hydroxyethyl methacrylate, ethylene glycol dimethacrylate,2-hydroxy-2-methyl-propiophenone, glycerol and N-vinyl-2-pyrrolidinone.

Preferably, a weight percentage concentration of the ingredients of thecomposition for manufacturing the hydrogel can be as follows. The weightpercentage concentration of the 2-hydroxyethyl methacrylate is 10% to96%, the weight percentage concentration of the ethylene glycoldimethacrylate is 0.01% to 5%, the weight percentage concentration ofthe 2-hydroxy-2-methyl-propiophenone is 0.01% to 5%, the weightpercentage concentration of the glycerol is 0.1% to 30%, and the weightpercentage concentration of the N-vinyl-2-pyrrolidinone is 0.1% to 25%.

More preferably, the weight percentage concentration of the ingredientsof the composition for manufacturing the hydrogel can be as follows. Theweight percentage concentration of the 2-hydroxyethyl methacrylate is40% to 96%, the weight percentage concentration of the ethylene glycoldimethacrylate is 0.1% to 2%, the weight percentage concentration of the2-hydroxy-2-methyl-propiophenone is 0.1% to 2%, the weight percentageconcentration of the glycerol is 1% to 20%, and the weight percentageconcentration of the N-vinyl-2-pyrrolidinone is 0.1% to 10%.

According to one example of the present disclosure, the composition formanufacturing the hydrogel can further include a blue-light blockingagent or a UV blocking agent. Preferably, a weight percentageconcentration of the blue-light blocking agent or the UV blocking agentof the composition for manufacturing the hydrogel is 0.01% to 10%. Morepreferably, the weight percentage concentration of the blue-lightblocking agent or the UV blocking agent for manufacturing thecomposition of the hydrogel is 0.1% to 5%.

By adjusting the ratio of the ingredients of the composition formanufacturing the hydrogel, a moisture content and a softness of themultifocal contact lens 110 can be effectively enhanced. Furthermore,the composition for manufacturing the hydrogel can selectively includeother ingredients according to practical needs. The monomers used in thecomposition for manufacturing the hydrogel and the monomers used in thecomposition for silicone hydrogel, such as 2-hydroxyethyl methacrylate,methacrylic acid, glycerol monomethacrylate, N-vinyl-2-pyrrolidinone,3-methacryloyloxypropyltris(trimethylsilyloxy)silane, N,N-dimethylacrylamide,3-(3-methacryloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methylsilane,(3-acryloxy-2-hydroxypropoxypropyl)terminated polydimethylsiloxane andmethyl methacrylate can be interchanged according to practical needs.

Referring back to FIG. 2, when a diameter of the central region 111 ofthe multifocal contact lens 110 is DiC, the following condition can besatisfied: 4 mm≤DiC≤10 mm. Therefore, the diameter can be flexiblyadjusted according to the pupil size of different physiological states,so that the accuracy for correcting myopia provided by the centralregion 111 can be enhanced, and the sight can be completely and clearlyfocused on retina. Preferably, the following condition can be satisfied:5 mm≤DiC≤9 mm.

When an outer diameter of the first annular region 112 of the multifocalcontact lens 110 is DiP1, the following condition can be satisfied: 6mm≤DiP1 ≤17 mm. Therefore, the outer diameter can be flexibly adjustedaccording to the size of palpebral fissure, so that a proper comfort andfitness of the multifocal contact lens 110 can be provided, and thewearing stability of the multifocal contact lens 110 can be enhanced.Preferably, the following condition can be satisfied: 7 mm≤DiP1 ≤15 mm.

When the diameter of the central region 111 of the multifocal contactlens 110 is DiC, and the outer diameter of the first annular region 112of the multifocal contact lens 110 is DiP1, the following condition canbe satisfied: 0.15≤DiC/DiP1 <1. Therefore, the value of DiC/DiP1 isproper, which is favorable to design the multifocal contact lens 110according to the physiological state of individual eyeball. Accordingly,it is favorable to correct myopia.

When a diopter of the central region 111 of the multifocal contact lens110 is PowC, the following condition can be satisfied: −6.00D≤PowC≤−0.25 D. Therefore, a proper correction for myopia can beprovided according to the need of users. Accordingly, a clear image canbe provided.

When a maximal diopter of the first annular region 112 of the multifocalcontact lens 110 is PowP1, the following condition can be satisfied:−5.50 D≤PowP1≤−0.50 D. Therefore, the maximal diopter of the firstannular region 112 can be properly designed, which is favorable tocorrect myopia.

When the diopter of the central region 111 of the multifocal contactlens 110 is PowC, and the maximal diopter of the first annular region112 of the multifocal contact lens 110 is PowP1, the following conditioncan be satisfied: |PowC−PowP1|≤12 D. Therefore, it is favorable tocorrect myopia. Furthermore, the increase degree of the diopter of thefirst annular region 112 can be moderated, so that the discomfortresulted from the excessive increase degree of the diopter can beavoided. Alternatively, the following condition can be satisfied:|PowC−PowP1|≤10D. Alternatively, the following condition can besatisfied: |PowC−PowP1|≤5 D. Alternatively, the following condition canbe satisfied: |PowC−PowP1|≤3 D. Alternatively, the following conditioncan be satisfied: |PowC−PowP1|≤2 D. Alternatively, the followingcondition can be satisfied: |PowC−PowP1|≤1.5 D. Alternatively, thefollowing condition can be satisfied: |PowC−PowP1|≤1 D. Alternatively,the following condition can be satisfied: |PowC−PowP1|≤0.5 D.Alternatively, the following condition can be satisfied:|PowC−PowP1|≤0.25 D.

FIG. 3 is a schematic plan view of a multifocal contact lens 210according to another embodiment of the present disclosure. Themultifocal contact lens 210 includes a central region 211, a firstannular region 212 and a second annular region 213. The central region211, the second annular region 213 and the first annular region 212 aresequentially connected from a center of the multifocal contact lens 210to a periphery of the multifocal contact lens 210 and are concentric. Adiameter of the central region 211 of the multifocal contact lens 210 isDiC, an outer diameter of the first annular region 212 of the multifocalcontact lens 210 is DiP1, and an outer diameter of the second annularregion 213 of the multifocal contact lens 210 is DiP2. A diopter of thesecond annular region 213 is different from a diopter of the centralregion 211, and a diopter of the first annular region 212 is differentfrom a diopter of the central region 211. Therefore, the multifocalcontact lens 210 is featured with multi-focus function, the peripheralsight can be focused in front of the retina, which can moderate theincrease of the axial length of the eyeball, and the exacerbation ofmyopia can be prevented. According to one example of the presentdisclosure, the diopter of the central region 211 is fixed.

At least one of the central region 211, the first annular region 212 andthe second annular region 213 of the multifocal contact lens 210 isaspheric. Therefore, it is favorable to design the first annular region212 and/or the second annular region 213 with a gradient diopter.

When the outer diameter of the second annular region 213 of themultifocal contact lens 210 is DiP2, the following condition can besatisfied: 5 mm≤DiP2≤13 mm. Therefore, the increase degree of thediopter can be moderated. Preferably, the following condition can besatisfied: 6 mm≤DiP2≤12 mm.

When the diameter of the central region 211 of the multifocal contactlens 210 is DiC, and the outer diameter of the second annular region 213of the multifocal contact lens 210 is DiP2, the following condition canbe satisfied: 0.2≤DiC/DiP2<1. Therefore, the increase degree of thediopter of the second annular region 213 can be moderated, so that thediscomfort resulted from the excessive increase degree of the dioptercan be avoided.

The other properties of the multifocal contact lens 210 can be the sameas that of the multifocal contact lens 110, and will not be repeatedherein.

FIG. 4 is a schematic plan view of a multifocal contact lens 310according to yet another embodiment of the present disclosure. Themultifocal contact lens 310 includes a central region 311, a firstannular region 312, a second annular region 313 and a third annularregion 314. The central region 311, the third annular region 314, thesecond annular region 313 and the first annular region 312 aresequentially connected from a center of the multifocal contact lens 310to a periphery of the multifocal contact lens 310 and are concentric. Adiameter of the central region 311 of the multifocal contact lens 310 isDiC, an outer diameter of the first annular region 312 of the multifocalcontact lens 310 is DiP1, an outer diameter of the second annular region313 of the multifocal contact lens 310 is DiP2, and an outer diameter ofthe third annular region 314 of the multifocal contact lens 310 is DiP3.A diopter of the third annular region 314 is different from a diopter ofthe central region 311, a diopter of the second annular region 313 isdifferent from a diopter of the central region 311, and a diopter of thefirst annular region 312 is different from a diopter of the centralregion 311. Therefore, the multifocal contact lens 310 is featured withmulti-focus function, the peripheral sight can be focused in front ofthe retina, which can moderate the increase of the axial length of theeyeball, and the exacerbation of myopia can be prevented. According toone example of the present disclosure, the diopter of the central region311 is fixed.

As shown in FIGS. 2-4, the multifocal contact lens (110, 210, 310)according to the present disclosure can have at least one annular region(the first annular region (112, 212, 312), the second annular region(213, 313), the third annular region (314)) concentrically surroundingthe central region (111, 211, 311). The number and the diopter of theannular region can be flexibly adjusted according to the physiologicalstate of individual eyeball, so that the effect of correcting myopia canbe enhanced. Accordingly, the myopia can be effectively prevented orcontrolled.

According to the present disclosure, another contact lens product isprovided. The contact lens product includes a multifocal contact lens. Acomposition for manufacturing the multifocal contact lens includes ablue-light blocking agent. Therefore, the multifocal contact lens canblock high-energy blue lights, and the probability that the retina hurtby the blue lights can be reduced. The details of the blue-lightblocking agent, the material and other properties of the multifocalcontact lens can refer to the content of FIGS. 1-4, and will not berepeated herein.

1 st EXAMPLE

In the 1st example, a multifocal contact lens includes a central regionand a first annular region. The first annular region concentricallysurrounds the central region. At least one of the central region and thefirst annular region is aspheric. The structure of the multifocalcontact lens of the 1st example can refer to FIG. 2.

In the multifocal contact lens of the 1st example, a diameter of thecentral region of the multifocal contact lens is DiC, an outer diameterof the first annular region of the multifocal contact lens is DiP1, adiopter of the central region of the multifocal contact lens is PowC, amaximal diopter of the first annular region of the multifocal contactlens is PowP1, the value of DiC, DiP1, DiC/DiP1, PowC, PowP1,|PowC−PowP1| of the 1st example are listed in Table 1.

TABLE 1 1st example DiC (mm) 5.00 PowC (D) −0.25 DiP1 (mm) 13.00 PowP1(D) 0.25 DiC/DiP1 0.38 |PowC − PowP1| (D) 0.50

Please refer to Table 2 and FIG. 5 simultaneously, radiuses and thecorrespondent diopters of the multifocal contact lens of the 1st exampleare listed in Table 2. FIG. 5 shows a relationship between the radiusand the diopter of the multifocal contact lens of the 1st example (thenegative radius having an opposite direction with the positive radius).As shown in Table 2 and FIG. 5, the diopter of the central region isfixed, and the diopter of the first annular region is different from thediopter of the central region. Specifically, the diopter of the firstannular region is greater than the diopter of the central region, andthe diopter of the first annular region increases when away from thecentral region.

TABLE 2 1st example radius (mm) diopter (D) −6.50 0.25 −6.00 0.19 −5.500.13 −5.00 0.06 −4.50 0.00 −4.00 −0.06 −3.50 −0.13 −3.00 −0.19 −2.50−0.25 −2.00 −0.25 −1.50 −0.25 −1.00 −0.25 −0.50 −0.25 0.00 −0.25 0.50−0.25 1.00 −0.25 1.50 −0.25 2.00 −0.25 2.50 −0.25 3.00 −0.19 3.50 −0.134.00 −0.06 4.50 0.00 5.00 0.06 5.50 0.13 6.00 0.19 6.50 0.25

In the 1st example, the multifocal contact lens is made of hydrogel. Acomposition for manufacturing the hydrogel of the 1st example is listedin Table 3.

TABLE 3 Ingredient Content (wt %) 2-hydroxyethyl methacrylate 822-(2′-hydroxy-5′-methacryloxyethylphenyl)- 1.2 2H-benzotriazole ethyleneglycol dimethacrylate 0.4 2-hydroxy-2-methyl-propiophenone 0.5 glycerol13.5 1,1,1-trimethylol propane trimethacrylate 0.2 methacrylic acid 2.2

As shown in Table 3, the multifocal contact lens of the 1st example canblock UV lights by adding2-(2′-hydroxy-5′-methacryloxyethylphenyl)-2H-benzotriazole.

2nd EXAMPLE

In the 2nd example, a multifocal contact lens includes a central region,a first annular region and a second annular region. The central region,the second annular region and the first annular region are sequentiallyconnected from a center of the multifocal contact lens to a periphery ofthe multifocal contact lens and are concentric. At least one of thecentral region, the second annular region, and the first annular regionis aspheric. The structure of the multifocal contact lens of the 2ndexample can refer to FIG. 3.

In the multifocal contact lens of the 2nd example, a diameter of thecentral region of the multifocal contact lens is DiC, an outer diameterof the first annular region of the multifocal contact lens is DiP1, anouter diameter of the second annular region of the multifocal contactlens is DiP2, a diopter of the central region of the multifocal contactlens is PowC, a maximal diopter of the first annular region of themultifocal contact lens is PowP1, a maximal diopter of the secondannular region of the multifocal contact lens is PowP2, the value ofDiC, DiP1, DiP2, DiC/DiP1, DiC/DiP2, PowC, PowP1, PowP2, |PowC−PowP1| ofthe 2nd example are listed in Table 4.

TABLE 4 2nd example DiC (mm) 5.00 PowC (D) −0.50 DiP1 (mm) 16.00 PowP1(D) 0.50 DiP2 (mm) 13.00 PowP2 (D) 0.50 DiC/DiP1 0.31 |PowC − PowP1| (D)1.00 DiC/DiP2 0.38

Please refer to Table 5 and FIG. 6 simultaneously, radiuses and thecorrespondent diopters of the multifocal contact lens of the 2nd exampleare listed in Table 5. FIG. 6 shows a relationship between the radiusand the diopter of the multifocal contact lens of the 2nd example (thenegative radius having an opposite direction with the positive radius).As shown in Table 5 and FIG. 6, the diopter of the central region isfixed, the diopter of the second annular region is different from thediopter of the central region, and the diopter of the first annularregion is different from the diopter of the central region.Specifically, the diopter of the second annular region is greater thanthe diopter of the central region, the diopter of the second annularregion increases when away from the central region, the diopter of thefirst annular region is greater than the diopter of the central region,and the diopter of the first annular region is fixed.

TABLE 5 2nd example radius (mm) diopter (D) −8.00 0.50 −7.50 0.50 −7.000.50 −6.50 0.50 −6.00 0.38 −5.50 0.25 −5.00 0.13 −4.50 0.00 −4.00 −0.13−3.50 −0.25 −3.00 −0.38 −2.50 −0.50 −2.00 −0.50 −1.50 −0.50 −1.00 −0.50−0.50 −0.50 0.00 −0.50 0.50 −0.50 1.00 −0.50 1.50 −0.50 2.00 −0.50 2.50−0.50 3.00 −0.38 3.50 −0.25 4.00 −0.13 4.50 0.00 5.00 0.13 5.50 0.256.00 0.38 6.50 0.50 7.00 0.50 7.50 0.50 8.00 0.50

In the 2nd example, the multifocal contact lens is made of hydrogel. Acomposition for manufacturing the hydrogel of the 2nd example is listedin Table 6A.

TABLE 6A Ingredient Content (wt %) 2-hydroxyethyl methacrylate 44.82-(2′-hydroxy-5′-methacryloxyethylphenyl)- 1.2 2H-benzotriazole ethyleneglycol dimethacrylate 0.6 2-hydroxy-2-methyl-propiophenone 0.6 glycerol10.5 1,1,1-trimethylol propane trimethacrylate 0.3 glycerolmonomethacrylate 42

As shown in Table 6A, the multifocal contact lens of the 2nd example canblock UV lights by adding2-(2′-hydroxy-5′-methacryloxyethylphenyl)-2H-benzotriazole.

FIG. 7 shows a relationship between a wavelength and a transmittance ofthe multifocal contact lens of the 2nd example and a multifocal contactlens of the 1st comparative example. The difference between the 1stcomparative example and the 2nd example is the 1st comparative examplein lack of UV blocking agent. Specifically, a composition of the 1stcomparative example is formulated by replacing the2-(2′-hydroxy-5′-methacryloxyethylphenyl)-2H-benzotriazole in the 2ndexample with the 2-hydroxyethyl methacrylate. In FIG. 7, a blocking ratefor UV-A (the UV lights with a wavelength ranging from 316 nm to 380 nm)of the 1st comparative example and the 2nd example can be calculated bythe following formula: (1−an average transmittance of the wavelengthranging from 316 nm to 380 nm)×100%. Furthermore, a blocking rate forUV-B (the UV lights with a wavelength ranging from 280 nm to 315 nm) ofthe 1st comparative example and the 2nd example can be calculated by thefollowing formula: (1−an average transmittance of the wavelength rangingfrom 280 nm to 315 nm)×100%. The calculated results are listed in Table6B.

TABLE 6B 1st comparative example 2nd example blocking rate for UV-A (%)5.92 73.19 (316 nm-380 nm) blocking rate for UV-B (%) 7.91 96.36 (280nm-315 nm)

As shown in Table 6B, comparing to the 1st comparative example, theblocking rate for UV-A and the blocking rate for UV-B of the 2nd exampleis much greater than that of the 1st comparative example. In otherwords, the multifocal contact lens of the 2nd example can effectivelyblock the UV lights, so that the probability that the retina hurt by theUV lights can be reduced.

3rd EXAMPLE

In the 3rd example, a multifocal contact lens includes a central region,a first annular region and a second annular region. The central region,the second annular region and the first annular region are sequentiallyconnected from a center of the multifocal contact lens to a periphery ofthe multifocal contact lens and are concentric. At least one of thecentral region, the second annular region, and the first annular regionis aspheric. The structure of the multifocal contact lens of the 3rdexample can refer to FIG. 3.

In the multifocal contact lens of the 3rd example, a diameter of thecentral region of the multifocal contact lens is DiC, an outer diameterof the first annular region of the multifocal contact lens is DiP1, anouter diameter of the second annular region of the multifocal contactlens is DiP2, a diopter of the central region of the multifocal contactlens is PowC, a maximal diopter of the first annular region of themultifocal contact lens is PowP1, a maximal diopter of the secondannular region of the multifocal contact lens is PowP2, the value ofDiC, DiP1, DiP2, DiC/DiP1, DiC/DiP2, PowC, PowP1, PowP2, |PowC−PowP1| ofthe 3rd example are listed in Table 7.

TABLE 7 3rd example DiC (mm) 4.00 PowC (D) −1.00 DiP1 (mm) 15.00 PowP1(D) 0.25 DiP2 (mm) 6.00 PowP2 (D) −0.50 DiC/DiP1 0.27 |PowC − PowP1| (D)1.25 DiC/DiP2 0.67

Please refer to Table 8 and FIG. 8 simultaneously, radiuses and thecorrespondent diopters of the multifocal contact lens of the 3rd exampleare listed in Table 8. FIG. 8 shows a relationship between the radiusand the diopter of the multifocal contact lens of the 3rd example (thenegative radius having an opposite direction with the positive radius).As shown in Table 8 and FIG. 8, the diopter of the central region isfixed, the diopter of the second annular region is different from thediopter of the central region, and the diopter of the first annularregion is different from the diopter of the central region.Specifically, the diopter of the second annular region is greater thanthe diopter of the central region, the diopter of the second annularregion increases when away from the central region, the diopter of thefirst annular region is greater than the diopter of the central region,and the diopter of the first annular region increases when away from thecentral region.

TABLE 8 3rd example radius (mm) diopter (D) −7.50 0.25 −7.00 0.17 −6.500.08 −6.00 0.00 −5.50 −0.08 −5.00 −0.17 −4.50 −0.25 −4.00 −0.33 −3.50−0.42 −3.00 −0.50 −2.50 −0.75 −2.00 −1.00 −1.50 −1.00 −1.00 −1.00 −0.50−1.00 0.00 −1.00 0.50 −1.00 1.00 −1.00 1.50 −1.00 2.00 −1.00 2.50 −0.753.00 −0.50 3.50 −0.42 4.00 −0.33 4.50 −0.25 5.00 −0.17 5.50 −0.08 6.000.00 6.50 0.08 7.00 0.17 7.50 0.25

In the 3rd example, the multifocal contact lens is made of hydrogel. Acomposition for manufacturing the hydrogel of the 3rd example is listedin Table 9.

TABLE 9 Content Ingredient (wt %) 2-hydroxyethyl methacrylate 912-(2′-hydroxy-5′-methacryloxyethylphenyl)-2H-benzotriazole 1 ethyleneglycol dimethacrylate 0.6 2-hydroxy-2-methyl-propiophenone 0.6 glycerol6.3 N-vinyl-2-pyrrolidinone 0.5

As shown in Table 9, the multifocal contact lens of the 3rd example canblock UV lights by adding2-(2′-hydroxy-5′-methacryloxyethylphenyl)-2H-benzotriazole.

4th EXAMPLE

In the 4th example, a multifocal contact lens includes a central regionand a first annular region. The first annular region concentricallysurrounds the central region. At least one of the central region and thefirst annular region is aspheric. The structure of the multifocalcontact lens of the 4th example can refer to FIG. 2.

In the multifocal contact lens of the 4th example, a diameter of thecentral region of the multifocal contact lens is DiC, an outer diameterof the first annular region of the multifocal contact lens is DiP1, adiopter of the central region of the multifocal contact lens is PowC, amaximal diopter of the first annular region of the multifocal contactlens is PowP1, the value of DiC, DiP1, DiC/DiP1, PowC, PowP1,|PowC−PowP1| of the 4th example are listed in Table 10.

TABLE 10 4th example DiC (mm) 7.00 PowC (D) −1.50 DiP1 (mm) 14.00 PowP1(D) −1.00 DiC/DiP1 0.50 |PowC − PowP1| (D) 0.50

Please refer to Table 11 and FIG. 9 simultaneously, radiuses and thecorrespondent diopters of the multifocal contact lens of the 4th exampleare listed in Table 11. FIG. 9 shows a relationship between the radiusand the diopter of the multifocal contact lens of the 4th example (thenegative radius having an opposite direction with the positive radius).As shown in Table 11 and FIG. 9, the diopter of the central region isfixed, and the diopter of the first annular region is different from thediopter of the central region. Specifically, the diopter of the firstannular region is greater than the diopter of the central region, andthe diopter of the first annular region increases when away from thecentral region.

TABLE 11 4th example radius (mm) diopter (D) −7.00 −1.00 −6.50 −1.07−6.00 −1.14 −5.50 −1.21 −5.00 −1.29 −4.50 −1.36 −4.00 −1.43 −3.50 −1.50−3.00 −1.50 −2.50 −1.50 −2.00 −1.50 −1.50 −1.50 −1.00 −1.50 −0.50 −1.500.00 −1.50 0.50 −1.50 1.00 −1.50 1.50 −1.50 2.00 −1.50 2.50 −1.50 3.00−1.50 3.50 −1.50 4.00 −1.43 4.50 −1.36 5.00 −1.29 5.50 −1.21 6.00 −1.146.50 −1.07 7.00 −1.00

In the 4th example, the multifocal contact lens is made of hydrogel. Acomposition for manufacturing the hydrogel of the 4th example is listedin Table 12A.

TABLE 12A Ingredient Content (wt %) 2-hydroxyethyl methacrylate 822-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate 1 ethylene glycoldimethacrylate 0.4 2-hydroxy-2-methyl-propiophenone 0.6 glycerol 13.61,1,1-trimethylol propane trimethacrylate 0.2 methacrylic acid 2.2

As shown in Table 12A, the multifocal contact lens of the 4th examplecan block UV lights by adding 2-(4-benzoyl-3-hydroxyphenoxy)ethylacrylate.

FIG. 10 shows a relationship between a wavelength and a transmittance ofthe multifocal contact lens of the 4th example and a multifocal contactlens of the 2nd comparative example. The difference between the 2ndcomparative example and the 4th example is the 2nd comparative examplein lack of UV blocking agent. Specifically, a composition of the 2ndcomparative example is formulated by replacing the2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate in the 4th example with the2-hydroxyethyl methacrylate. In FIG. 10, a blocking rate for UV-A (theUV lights with a wavelength ranging from 316 nm to 380 nm) of the 2ndcomparative example and the 4th example can be calculated by thefollowing formula: (1−an average transmittance of the wavelength rangingfrom 316 nm to 380 nm)×100%. Furthermore, a blocking rate for UV-B (theUV lights with a wavelength ranging from 280 nm to 315 nm) of the 2ndcomparative example and the 4th example can be calculated by thefollowing formula: (1−an average transmittance of the wavelength rangingfrom 280 nm to 315 nm)×100%. The calculated results are listed in Table12B.

TABLE 12B 2nd comparative example 4th example blocking rate for UV-A6.44 79.32 (%) (316 nm-380 nm) blocking rate for UV-B 8.76 98.39 (%)(280 nm-315 nm)

As shown in Table 12B, comparing to the 2nd comparative example, theblocking rate for UV-A and the blocking rate for UV-B of the 4th exampleis much greater than that of the 2nd comparative example. In otherwords, the multifocal contact lens of the 4th example can effectivelyblock the UV lights, so that the probability that the retina hurt by theUV lights can be reduced.

5th EXAMPLE

In the 5th example, a multifocal contact lens includes a central region,a first annular region and a second annular region. The central region,the second annular region and the first annular region are sequentiallyconnected from a center of the multifocal contact lens to a periphery ofthe multifocal contact lens and are concentric. At least one of thecentral region, the second annular region, and the first annular regionis aspheric. The structure of the multifocal contact lens of the 5thexample can refer to FIG. 3.

In the multifocal contact lens of the 5th example, a diameter of thecentral region of the multifocal contact lens is DiC, an outer diameterof the first annular region of the multifocal contact lens is DiP1, anouter diameter of the second annular region of the multifocal contactlens is DiP2, a diopter of the central region of the multifocal contactlens is PowC, a maximal diopter of the first annular region of themultifocal contact lens is PowP1, a maximal diopter of the secondannular region of the multifocal contact lens is PowP2, the value ofDiC, DiP1, DiP2, DiC/DiP1, DiC/DiP2, PowC, PowP1, PowP2, |PowC−PowP1| ofthe 5th example are listed in Table 13.

TABLE 13 5th example DiC (mm) 8.00 PowC (D) −2.00 DiP1 (mm) 15.00 PowP1(D) 0 DiP2 (mm) 11.00 PowP2 (D) 0 DiC/DiP1 0.53 |PowC − PowP1| (D) 2.00DiC/DiP2 0.73

Please refer to Table 14 and FIG. 11 simultaneously, radiuses and thecorrespondent diopters of the multifocal contact lens of the 5th exampleare listed in Table 14. FIG. 11 shows a relationship between the radiusand the diopter of the multifocal contact lens of the 5th example (thenegative radius having an opposite direction with the positive radius).As shown in Table 14 and FIG. 11, the diopter of the central region isfixed, the diopter of the second annular region is different from thediopter of the central region, and the diopter of the first annularregion is different from the diopter of the central region.Specifically, the diopter of the second annular region is greater thanthe diopter of the central region, the diopter of the second annularregion increases when away from the central region, the diopter of thefirst annular region is greater than the diopter of the central region,and the diopter of the first annular region is fixed.

TABLE 14 5th example radius (mm) diopter (D) −7.50 0.00 −7.00 0.00 −6.500.00 −6.00 0.00 −5.50 0.00 −5.00 −0.67 −4.50 −1.33 −4.00 −2.00 −3.50−2.00 −3.00 −2.00 −2.50 −2.00 −2.00 −2.00 −1.50 −2.00 −1.00 −2.00 −0.50−2.00 0.00 −2.00 0.50 −2.00 1.00 −2.00 1.50 −2.00 2.00 −2.00 2.50 −2.003.00 −2.00 3.50 −2.00 4.00 −2.00 4.50 −1.33 5.00 −0.67 5.50 0.00 6.000.00 6.50 0.00 7.00 0.00 7.50 0.00

In the 5th example, the multifocal contact lens is made of hydrogel. Acomposition for manufacturing the hydrogel of the 5th example is listedin Table 15.

TABLE 15 Ingredient Content (wt %) 2-hydroxyethyl methacrylate 452-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate 0.9 ethylene glycoldimethacrylate 0.6 2-hydroxy-2-methyl-propiophenone 0.6 glycerol 10.61,1,1-trimethylol propane trimethacrylate 0.3 glycerol monomethacrylate42

As shown in Table 15, the multifocal contact lens of the 5th example caneffectively block the UV lights by adding2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate.

6th EXAMPLE

In the 6th example, a multifocal contact lens includes a central regionand a first annular region. The first annular region concentricallysurrounds the central region. At least one of the central region and thefirst annular region is aspheric. The structure of the multifocalcontact lens of the 6th example can refer to FIG. 2.

In the multifocal contact lens of the 6th example, a diameter of thecentral region of the multifocal contact lens is DiC, an outer diameterof the first annular region of the multifocal contact lens is DiP1, adiopter of the central region of the multifocal contact lens is PowC, amaximal diopter of the first annular region of the multifocal contactlens is PowP1, the value of DiC, DiP1, DiC/DiP1, PowC, PowP1,|PowC−PowP1| of the 6th example are listed in Table 16.

TABLE 16 6th example DiC (mm) 9.00 PowC (D) −2.50 DiP1 (mm) 14.00 PowP1(D) −2.25 DiC/DiP1 0.64 |PowC − PowP1| (D) 0.25

Please refer to Table 17 and FIG. 12 simultaneously, radiuses and thecorrespondent diopters of the multifocal contact lens of the 6th exampleare listed in Table 17. FIG. 12 shows a relationship between the radiusand the diopter of the multifocal contact lens of the 6th example (thenegative radius having an opposite direction with the positive radius).As shown in Table 17 and FIG. 12, the diopter of the central region isfixed, and the diopter of the first annular region is different from thediopter of the central region. Specifically, the diopter of the firstannular region is greater than the diopter of the central region, andthe diopter of the first annular region increases when away from thecentral region.

TABLE 17 6th example radius (mm) diopter (D) −7.00 −2.25 −6.50 −2.30−6.00 −2.35 −5.50 −2.40 −5.00 −2.45 −4.50 −2.50 −4.00 −2.50 −3.50 −2.50−3.00 −2.50 −2.50 −2.50 −2.00 −2.50 −1.50 −2.50 −1.00 −2.50 −0.50 −2.500.00 −2.50 0.50 −2.50 1.00 −2.50 1.50 −2.50 2.00 −2.50 2.50 −2.50 3.00−2.50 3.50 −2.50 4.00 −2.50 4.50 −2.50 5.00 −2.45 5.50 −2.40 6.00 −2.356.50 −2.30 7.00 −2.25

In the 6th example, the multifocal contact lens is made of hydrogel. Acomposition for manufacturing the hydrogel of the 6th example is listedin Table 18.

TABLE 18 Ingredient Content (wt %) 2-hydroxyethyl methacrylate 90.42-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate 1.2 ethylene glycoldimethacrylate 0.6 2-hydroxy-2-methyl-propiophenone 0.7 glycerol 6.3N-vinyl-2-pyrrolidinone 0.8

As shown in Table 18, the multifocal contact lens of the 6th example caneffectively block the UV lights by adding2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate.

7th EXAMPLE

In the 7th example, a multifocal contact lens includes a central region,a first annular region and a second annular region. The central region,the second annular region and the first annular region are sequentiallyconnected from a center of the multifocal contact lens to a periphery ofthe multifocal contact lens and are concentric. At least one of thecentral region, the second annular region, and the first annular regionis aspheric. The structure of the multifocal contact lens of the 7thexample can refer to FIG. 3.

In the multifocal contact lens of the 7th example, a diameter of thecentral region of the multifocal contact lens is DiC, an outer diameterof the first annular region of the multifocal contact lens is DiP1, anouter diameter of the second annular region of the multifocal contactlens is DiP2, a diopter of the central region of the multifocal contactlens is PowC, a maximal diopter of the first annular region of themultifocal contact lens is PowP1, a maximal diopter of the secondannular region of the multifocal contact lens is PowP2, the value ofDiC, DiP1, DiP2, DiC/DiP1, DiC/DiP2, PowC, PowP1, PowP2, |PowC−PowP1| ofthe 7th example are listed in Table 19.

TABLE 19 7th example DiC (mm) 4.00 PowC (D) −3.00 DiP1 (mm) 15.00 PowP1(D) −1.00 DiP2 (mm) 8.00 PowP2 (D) −2.00 DiC/DiP1 0.27 |PowC − PowP1|(D) 2.00 DiC/DiP2 0.50

Please refer to Table 20 and FIG. 13 simultaneously, radiuses and thecorrespondent diopters of the multifocal contact lens of the 7th exampleare listed in Table 20. FIG. 13 shows a relationship between the radiusand the diopter of the multifocal contact lens of the 7th example (thenegative radius having an opposite direction with the positive radius).As shown in Table 20 and FIG. 13, the diopter of the central region isfixed, the diopter of the second annular region is different from thediopter of the central region, and the diopter of the first annularregion is different from the diopter of the central region.Specifically, the diopter of the second annular region is greater thanthe diopter of the central region, the diopter of the second annularregion increases when away from the central region, the diopter of thefirst annular region is greater than the diopter of the central region,and the diopter of the first annular region increases when away from thecentral region.

TABLE 20 7th example radius (mm) diopter (D) −7.50 −1.00 −7.00 −1.14−6.50 −1.29 −6.00 −1.43 −5.50 −1.57 −5.00 −1.71 −4.50 −1.86 −4.00 −2.00−3.50 −2.25 −3.00 −2.50 −2.50 −2.75 −2.00 −3.00 −1.50 −3.00 −1.00 −3.00−0.50 −3.00 0.00 −3.00 0.50 −3.00 1.00 −3.00 1.50 −3.00 2.00 −3.00 2.50−2.75 3.00 −2.50 3.50 −2.25 4.00 −2.00 4.50 −1.86 5.00 −1.71 5.50 −1.576.00 −1.43 6.50 −1.29 7.00 −1.14 7.50 −1.00

In the 7th example, the multifocal contact lens is made of hydrogel. Acomposition for manufacturing the hydrogel of the 7th example is listedin Table 21A.

TABLE 21A Ingredient Content (wt %) 2-hydroxyethyl methacrylate 824-(phenyldiazenyl) phenyl methacrylate 1 ethylene glycol dimethacrylate0.4 2-hydroxy-2-methyl-propiophenone 0.6 glycerol 13.5 1,1,1-trimethylolpropane trimethacrylate 0.2 methacrylic acid 2.3

As shown in Table 21A, the multifocal contact lens of the 7th examplecan effectively block the blue lights by adding 4-(phenyldiazenyl)phenyl methacrylate.

FIG. 14 shows a relationship between a wavelength and a transmittance ofthe multifocal contact lens of the 7th example and a multifocal contactlens the 3rd comparative example. The difference between the 3rdcomparative example and the 7th example is the 3rd comparative examplein lack of blue-light blocking agent. Specifically, a composition of the3rd comparative example is formulated by replacing the4-(phenyldiazenyl) phenyl methacrylate in the 7th example with the2-hydroxyethyl methacrylate. In FIG. 14, a blocking rate for blue lights(with a wavelength ranging from 380 nm to 495 nm) of the 3rd comparativeexample and the 7th example can be calculated by the following formula:(1−an average transmittance of the wavelength ranging from 380 nm to 495nm)×100%. The calculated results are listed in Table 21B.

TABLE 21B 3rd comparative example 7th example blocking rate for blue8.21 35.53 lights (%) (380 nm-495 nm)

As shown in Table 21B, comparing to the 3rd comparative example, theblocking rate for blue lights of the 7th example is much greater thanthat of the 3rd comparative example. In other words, the multifocalcontact lens of the 7th example can effectively block the blue lights,so that the probability that the retina hurt by the blue lights can bereduced.

8th EXAMPLE

In the 8th example, a multifocal contact lens includes a central regionand a first annular region. The first annular region concentricallysurrounds the central region. At least one of the central region and thefirst annular region is aspheric. The structure of the multifocalcontact lens of the 8th example can refer to FIG. 2.

In the multifocal contact lens of the 8th example, a diameter of thecentral region of the multifocal contact lens is DiC, an outer diameterof the first annular region of the multifocal contact lens is DiP1, adiopter of the central region of the multifocal contact lens is PowC, amaximal diopter of the first annular region of the multifocal contactlens is PowP1, the value of DiC, DiP1, DiC/DiP1, PowC, PowP1,|PowC−PowP1| of the 8th example are listed in Table 22.

TABLE 22 8th example DiC (mm) 5.00 PowC (D) −3.50 DiP1 (mm) 10.00 PowP1(D) −1.75 DiC/DiP1 0.50 |PowC − PowP1| (D) 1.75

Please refer to Table 23 and FIG. 15 simultaneously, radiuses and thecorrespondent diopters of the multifocal contact lens of the 8th exampleare listed in Table 23. FIG. 15 shows a relationship between the radiusand the diopter of the multifocal contact lens of the 8th example (thenegative radius having an opposite direction with the positive radius).As shown in Table 23 and FIG. 15, the diopter of the central region isfixed, and the diopter of the first annular region is different from thediopter of the central region. Specifically, the diopter of the firstannular region is greater than the diopter of the central region, andthe diopter of the first annular region increases when away from thecentral region.

TABLE 23 8th example radius (mm) diopter (D) −5.00 −1.75 −4.50 −2.10−4.00 −2.45 −3.50 −2.80 −3.00 −3.15 −2.50 −3.50 −2.00 −3.50 −1.50 −3.50−1.00 −3.50 −0.50 −3.50 0.00 −3.50 0.50 −3.50 1.00 −3.50 1.50 −3.50 2.00−3.50 2.50 −3.50 3.00 −3.15 3.50 −2.80 4.00 −2.45 4.50 −2.10 5.00 −1.75

In the 8th example, the multifocal contact lens is made of hydrogel. Acomposition for manufacturing the hydrogel of the 8th example is listedin Table 24.

TABLE 24 Ingredient Content (wt %) 2-hydroxyethyl methacrylate 454-(phenyldiazenyl) phenyl methacrylate 1 ethylene glycol dimethacrylate0.5 2-hydroxy-2-methyl-propiophenone 0.6 glycerol 10.6 1,1,1-trimethylolpropane trimethacrylate 0.3 glycerol monomethacrylate 42

As shown in Table 24, the multifocal contact lens of the 8th example caneffectively block the blue lights by adding 4-(phenyldiazenyl) phenylmethacrylate.

9th EXAMPLE

In the 9th example, a multifocal contact lens includes a central region,a first annular region and a second annular region. The central region,the second annular region and the first annular region are sequentiallyconnected from a center of the multifocal contact lens to a periphery ofthe multifocal contact lens and are concentric. At least one of thecentral region, the second annular region, and the first annular regionis aspheric. The structure of the multifocal contact lens of the 9thexample can refer to FIG. 3.

In the multifocal contact lens of the 9th example, a diameter of thecentral region of the multifocal contact lens is DiC, an outer diameterof the first annular region of the multifocal contact lens is DiP1, anouter diameter of the second annular region of the multifocal contactlens is DiP2, a diopter of the central region of the multifocal contactlens is PowC, a maximal diopter of the first annular region of themultifocal contact lens is PowP1, a maximal diopter of the secondannular region of the multifocal contact lens is PowP2, the value ofDiC, DiP1, DiP2, DiC/DiP1, DiC/DiP2, PowC, PowP1, PowP2, |PowC−PowP1| ofthe 9th example are listed in Table 25.

TABLE 25 9th example DiC (mm) 6.00 PowC (D) −4.00 DiP1 (mm) 14.00 PowP1(D) −3.25 DiP2 (mm) 10.00 PowP2 (D) −3.75 DiC/DiP1 0.43 |PowC − PowP1|(D) 0.75 DiC/DiP2 0.60

Please refer to Table 26 and FIG. 16 simultaneously, radiuses and thecorrespondent diopters of the multifocal contact lens of the 9th exampleare listed in Table 26. FIG. 16 shows a relationship between the radiusand the diopter of the multifocal contact lens of the 9th example (thenegative radius having an opposite direction with the positive radius).As shown in Table 26 and FIG. 16, the diopter of the central region isfixed, the diopter of the second annular region is different from thediopter of the central region, and the diopter of the first annularregion is different from the diopter of the central region.Specifically, the diopter of the second annular region is greater thanthe diopter of the central region, the diopter of the second annularregion increases when away from the central region, the diopter of thefirst annular region is greater than the diopter of the central region,and the diopter of the first annular region increases when away from thecentral region.

TABLE 26 9th example radius (mm) diopter (D) −7.00 −3.25 −6.50 −3.38−6.00 −3.50 −5.50 −3.63 −5.00 −3.75 −4.50 −3.81 −4.00 −3.88 −3.50 −3.94−3.00 −4.00 −2.50 −4.00 −2.00 −4.00 −1.50 −4.00 −1.00 −4.00 −0.50 −4.000.00 −4.00 0.50 −4.00 1.00 −4.00 1.50 −4.00 2.00 −4.00 2.50 −4.00 3.00−4.00 3.50 −3.94 4.00 −3.88 4.50 −3.81 5.00 −3.75 5.50 −3.63 6.00 −3.506.50 −3.38 7.00 −3.25

In the 9th example, the multifocal contact lens is made of hydrogel. Acomposition for manufacturing the hydrogel of the 9th example is listedin Table 27.

TABLE 27 Ingredient Content (wt %) 2-hydroxyethyl methacrylate 90.34-(phenyldiazenyl) phenyl methacrylate 1.2 ethylene glycoldimethacrylate 0.6 2-hydroxy-2-methyl-propiophenone 0.6 glycerol 6.5N-vinyl-2-pyrrolidinone 0.8

As shown in Table 27, the multifocal contact lens of the 9th example caneffectively block the blue lights by adding 4-(phenyldiazenyl) phenylmethacrylate.

10th EXAMPLE

In the 10th example, a multifocal contact lens includes a central regionand a first annular region. The first annular region concentricallysurrounds the central region. At least one of the central region and thefirst annular region is aspheric. The structure of the multifocalcontact lens of the 10th example can refer to FIG. 2.

In the multifocal contact lens of the 10th example, a diameter of thecentral region of the multifocal contact lens is DiC, an outer diameterof the first annular region of the multifocal contact lens is DiP1, adiopter of the central region of the multifocal contact lens is PowC, amaximal diopter of the first annular region of the multifocal contactlens is PowP1, the value of DiC, DiP1, DiC/DiP1, PowC, PowP1,|PowC−PowP1| of the 10th example are listed in Table 28.

TABLE 28 10th example DiC (mm) 7.00 PowC (D) −4.50 DiP1 (mm) 12.00 PowP1(D) −3.00 DiC/DiP1 0.58 |PowC − PowP1| (D) 1.50

Please refer to Table 29 and FIG. 17 simultaneously, radiuses and thecorrespondent diopters of the multifocal contact lens of the 10thexample are listed in Table 29. FIG. 17 shows a relationship between theradius and the diopter of the multifocal contact lens of the 10thexample (the negative radius having an opposite direction with thepositive radius). As shown in Table 29 and FIG. 17, the diopter of thecentral region is fixed, and the diopter of the first annular region isdifferent from the diopter of the central region. Specifically, thediopter of the first annular region is greater than the diopter of thecentral region, and the diopter of the first annular region increaseswhen away from the central region.

TABLE 29 10th example radius (mm) diopter (D) −6.00 −3.00 −5.50 −3.30−5.00 −3.60 −4.50 −3.90 −4.00 −4.20 −3.50 −4.50 −3.00 −4.50 −2.50 −4.50−2.00 −4.50 −1.50 −4.50 −1.00 −4.50 −0.50 −4.50 0.00 −4.50 0.50 −4.501.00 −4.50 1.50 −4.50 2.00 −4.50 2.50 −4.50 3.00 −4.50 3.50 −4.50 4.00−4.20 4.50 −3.90 5.00 −3.60 5.50 −3.30 6.00 −3.00

In the 10th example, the multifocal contact lens is made of siliconehydrogel. A composition for manufacturing the silicone hydrogel of the10th example is listed in Table 30.

TABLE 30 Content Ingredient (wt %) 2-hydroxyethyl methacrylate 4.33-methacryloyloxypropyltris(trimethylsilyloxy)silane 282-hydroxy-2-methyl-propiophenone 0.6 N-vinyl-2-pyrrolidinone 20.2N,N-dimethyl acrylamide 12.3 ethylene glycol dimethacrylate 0.62-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate 1 3-(3-methacryloxy-2- 21.5hydroxypropoxy)propylbis(trimethylsiloxy)methylsilane isopropyl alcohol10 methacrylic acid 1.5

As shown in Table 30, the multifocal contact lens of the 10th examplecan effectively block the UV lights by adding2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate.

11th EXAMPLE

In the 11th example, a multifocal contact lens includes a centralregion, a first annular region and a second annular region. The centralregion, the second annular region and the first annular region aresequentially connected from a center of the multifocal contact lens to aperiphery of the multifocal contact lens and are concentric. At leastone of the central region, the second annular region, and the firstannular region is aspheric. The structure of the multifocal contact lensof the 11th example can refer to FIG. 3.

In the multifocal contact lens of the 11th example, a diameter of thecentral region of the multifocal contact lens is DiC, an outer diameterof the first annular region of the multifocal contact lens is DiP1, anouter diameter of the second annular region of the multifocal contactlens is DiP2, a diopter of the central region of the multifocal contactlens is PowC, a maximal diopter of the first annular region of themultifocal contact lens is PowP1, a maximal diopter of the secondannular region of the multifocal contact lens is PowP2, the value ofDiC, DiP1, DiP2, DiC/DiP1, DiC/DiP2, PowC, PowP1, PowP2, |PowC−PowP1| ofthe 11th example are listed in Table 31.

TABLE 31 11th example DiC (mm) 8.00 PowC (D) −5.00 DiP1 (mm) 13.00 PowP1(D) −2.75 DiP2 (mm) 10.00 PowP2 (D) −4.00 DiC/DiP1 0.62 |PowC − PowP1|(D) 2.25 DiC/DiP2 0.80

Please refer to Table 32 and FIG. 18 simultaneously, radiuses and thecorrespondent diopters of the multifocal contact lens of the 11thexample are listed in Table 32. FIG. 18 shows a relationship between theradius and the diopter of the multifocal contact lens of the 11thexample (the negative radius having an opposite direction with thepositive radius). As shown in Table 32 and FIG. 18, the diopter of thecentral region is fixed, the diopter of the second annular region isdifferent from the diopter of the central region, and the diopter of thefirst annular region is different from the diopter of the centralregion. Specifically, the diopter of the second annular region isgreater than the diopter of the central region, the diopter of thesecond annular region increases when away from the central region, thediopter of the first annular region is greater than the diopter of thecentral region, and the diopter of the first annular region increaseswhen away from the central region.

TABLE 32 11th example radius (mm) diopter (D) −6.50 −2.75 −6.00 −3.17−5.50 −3.58 −5.00 −4.00 −4.50 −4.50 −4.00 −5.00 −3.50 −5.00 −3.00 −5.00−2.50 −5.00 −2.00 −5.00 −1.50 −5.00 −1.00 −5.00 −0.50 −5.00 0.00 −5.000.50 −5.00 1.00 −5.00 1.50 −5.00 2.00 −5.00 2.50 −5.00 3.00 −5.00 3.50−5.00 4.00 −5.00 4.50 −4.50 5.00 −4.00 5.50 −3.58 6.00 −3.17 6.50 −2.75

In the 11th example, the multifocal contact lens is made of siliconehydrogel. A composition for manufacturing the silicone hydrogel of the11th example is listed in Table 33A.

TABLE 33A Ingredient Content (wt %) 2-hydroxyethyl methacrylate 43-methacryloyloxypropyltris(trimethylsilyloxy)silane 282-hydroxy-2-methyl-propiophenone 0.6 N-vinyl-2-pyrrolidinone 20.5N,N-dimethyl acrylamide 12.3 ethylene glycol dimethacrylate 0.52-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate 1.1(3-acryloxy-2-hydroxypropoxypropyl)terminated 22 polydimethylsiloxane1-hexanol 11

As shown in Table 33A, the multifocal contact lens of the 11th examplecan effectively block the UV lights by adding2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate.

FIG. 19 shows a relationship between a wavelength and a transmittance ofthe multifocal contact lens of the 11th example and a multifocal contactlens the 4th comparative example. The difference between the 4thcomparative example and the 11th example is the 4th comparative examplein lack of UV blocking agent. Specifically, a composition of the 4thcomparative example is formulated by replacing the2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate in the 11th example withthe 2-hydroxyethyl methacrylate. In FIG. 19, a blocking rate for UV-A(the UV lights with a wavelength ranging from 316 nm to 380 nm) of the4th comparative example and the 11th example can be calculated by thefollowing formula: (1−an average transmittance of the wavelength rangingfrom 316 nm to 380 nm)×100%. Furthermore, a blocking rate for UV-B (theUV lights with a wavelength ranging from 280 nm to 315 nm) of the 4thcomparative example and the 11th example can be calculated by thefollowing formula: (1−an average transmittance of the wavelength rangingfrom 280 nm to 315 nm)×100%. The calculated results are listed in Table33B.

TABLE 33B 4th comparative 11th example example blocking rate 15.02 90.01for UV-A (%) (316 nm-380 nm) blocking rate 40.91 99.24 for UV-B (%) (280nm-315 nm)

As shown in Table 33B, comparing to the 4th comparative example, theblocking rate for UV-A and the blocking rate for UV-B of the 11thexample is much greater than that of the 4th comparative example. Inother words, the multifocal contact lens of the 11th example caneffectively block the UV lights, so that the probability that the retinahurt by the UV lights can be reduced.

12th EXAMPLE

In the 12th example, a multifocal contact lens includes a centralregion, a first annular region, a second annular region and a thirdannular region. The central region, the third annular region, the secondannular region and the first annular region are sequentially connectedfrom a center of the multifocal contact lens to a periphery of themultifocal contact lens and are concentric. At least one of the centralregion, the third annular region, the second annular region and thefirst annular region is aspheric. The structure of the multifocalcontact lens of the 12th example can refer to FIG. 4.

In the multifocal contact lens of the 12th example, a diameter of thecentral region of the multifocal contact lens is DiC, an outer diameterof the first annular region of the multifocal contact lens is DiP1, anouter diameter of the second annular region of the multifocal contactlens is DiP2, an outer diameter of the third annular region of themultifocal contact lens is DiP3, a diopter of the central region of themultifocal contact lens is PowC, a maximal diopter of the first annularregion of the multifocal contact lens is PowP1, a maximal diopter of thesecond annular region of the multifocal contact lens is PowP2, a maximaldiopter of the third annular region of the multifocal contact lens isPowP3, the value of DiC, DiP1, DiP2, DiP3, DiC/DiP1, DiC/DiP2, PowC,PowP1, PowP2, PowP3, |PowC−PowP1| of the 12th example are listed inTable 34.

TABLE 34 12th example DiC (mm) 4.00 PowC (D) −5.50 DiP1 (mm) 16.00 PowP1(D) −3.00 DiP2 (mm) 12.00 PowP2 (D) −3.00 DiP3 (mm) 8.00 PowP3 (D) −3.75DiC/DiP1 0.25 |PowC − PowP1| (D) 2.50 DiC/DiP2 0.33

Please refer to Table 35 and FIG. 20 simultaneously, radiuses and thecorrespondent diopters of the multifocal contact lens of the 12thexample are listed in Table 35. FIG. 20 shows a relationship between theradius and the diopter of the multifocal contact lens of the 12thexample (the negative radius having an opposite direction with thepositive radius). As shown in Table 35 and FIG. 20, the diopter of thecentral region is fixed, the diopter of the third annular region isdifferent from the diopter of the central region, the diopter of thesecond annular region is different from the diopter of the centralregion, and the diopter of the first annular region is different fromthe diopter of the central region. Specifically, the diopter of thethird annular region is greater than the diopter of the central region,the diopter of the third annular region increases when away from thecentral region, the diopter of the second annular region is greater thanthe diopter of the central region, the diopter of the second annularregion increases when away from the central region, the diopter of thefirst annular region is greater than the diopter of the central region,and the diopter of the first annular region is fixed.

TABLE 35 12th example radius (mm) diopter (D) −8.00 −3.00 −7.50 −3.00−7.00 −3.00 −6.50 −3.00 −6.00 −3.00 −5.50 −3.19 −5.00 −3.38 −4.50 −3.56−4.00 −3.75 −3.50 −4.19 −3.00 −4.63 −2.50 −5.06 −2.00 −5.50 −1.50 −5.50−1.00 −5.50 −0.50 −5.50 0.00 −5.50 0.50 −5.50 1.00 −5.50 1.50 −5.50 2.00−5.50 2.50 −5.06 3.00 −4.63 3.50 −4.19 4.00 −3.75 4.50 −3.56 5.00 −3.385.50 −3.19 6.00 −3.00 6.50 −3.00 7.00 −3.00 7.50 −3.00 8.00 −3.00

In the 12th example, the multifocal contact lens is made of siliconehydrogel. A composition for manufacturing the silicone hydrogel of the12th example is listed in Table 36A.

TABLE 36A Ingredient Content (wt %) 2-hydroxyethyl methacrylate 4.23-methacryloyloxypropyltris(trimethylsilyloxy)silane 262-hydroxy-2-methyl-propiophenone 0.6 N-vinyl-2-pyrrolidinone 20N,N-dimethyl acrylamide 11 polysiloxane macromer 24 4-(phenyldiazenyl)phenyl methacrylate 1 methyl methacrylate 4.2 ethanol 9

As shown in Table 36A, the multifocal contact lens of the 12th examplecan effectively block the blue lights by adding 4-(phenyldiazenyl)phenyl methacrylate.

FIG. 21 shows a relationship between a wavelength and a transmittance ofthe multifocal contact lens of the 12th example and a multifocal contactlens the 5th comparative example. The difference between the 5thcomparative example and the 12th example is the 5th comparative examplein lack of blue-light blocking agent. Specifically, a composition of the5th comparative example is formulated by replacing the4-(phenyldiazenyl) phenyl methacrylate in the 12th example with the2-hydroxyethyl methacrylate. In FIG. 21, a blocking rate for blue lights(with a wavelength ranging from 380 nm to 495 nm) of the 5th comparativeexample and the 12th example can be calculated by the following formula:(1−an average transmittance of the wavelength ranging from 380 nm to 495nm)×100%. The calculated results are listed in Table 36B.

TABLE 36B 5th comparative example 12th example blocking rate for blue10.31 16.32 lights (%) (380 nm-495 nm)

As shown in Table 36B, comparing to the 5th comparative example, theblocking rate for blue lights of the 12th example is much greater thanthat of the 5th comparative example. In other words, the multifocalcontact lens of the 12th example can effectively block the blue lights,so that the probability that the retina hurt by the blue lights can bereduced.

According to the multifocal contact lens of the present disclosure, aaspheric surface refers to a curved shape of a front surface or a backsurface shown in a cross-sectional view taken along the central line ofthe multifocal contact lens. The front surface is a surface of themultifocal contact lens far away from the cornea, and the back surfaceis a surface of the multifocal contact lens close to the cornea.

According to the multifocal contact lens of the present disclosure, thediopter is represented by D. When the multifocal contact lens is forcorrecting myopia, the diopter thereof is negative; when the multifocalcontact lens is for correcting hyperopia, the diopter thereof ispositive.

According to the present disclosure, the cycloplegic agent can includebut is not limited to atropine((3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl tropate), tropicamide(N-ethyl-3-hydroxy-2-phenyl-N-(4-pyridinylmethyl)propanamide),cyclopentolate (2-(dimethylamino)ethyl(1-hydroxycyclopentyl)(phenyl)acetate), homatropine((3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl hydroxy(phenyl)acetate),scopolamine((1R,2R,4S,5S,7S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0^(2,4)]non-7-yl(2S)-3-hydroxy-2-phenylpropanoate),eucatropine (1,2,2,6-tetramethyl-4-piperidinyl hydroxy(phenyl)acetate)or the salt thereof. The cycloplegic agent, also known as a mydriaticagent, belongs to a parasympathetic blocker, i.e., a non-selectivem-type muscarinic receptor blocker, which can control the paralysis andrelaxation of the ciliary muscle of pupils by blocking the muscarinicreceptor so as to enlarge the pupil.

It will be apparent to those skilled in the art that variousmodifications and variations can be made to the structure of the presentdisclosure without departing from the scope or spirit of the disclosure.In view of the foregoing, it is intended that the present disclosurecover modifications and variations of this disclosure provided they fallwithin the scope of the following claims.

What is claimed is:
 1. A contact lens product, configured to preventmyopia or control a progression of myopia, comprising: a multifocalcontact lens, comprising: a central region; and at least one annularregion concentrically surrounding the central region, wherein a diopterof the annular region is different from a diopter of the central region;and a buffer solution, wherein the multifocal contact lens is immersedin the buffer solution, the buffer solution comprises a cycloplegicagent, a weight percentage concentration of the cycloplegic agent in thebuffer solution is ConA, a diameter of the central region of themultifocal contact lens is DiC, a diopter of the central region of themultifocal contact lens is PowC, a maximum diopter of the first annularregion of the multifocal contact lens is PowP1, and the followingconditions are satisfied:0.01%≤ConA<0.5%;4 mm<DiC; and2.25 D≤PowP1−PowC.
 2. The contact lens product of claim 1, wherein theweight percentage concentration of the cycloplegic agent in the buffersolution is ConA, and the following condition is satisfied:0. 01≤ConA≤0.25%.
 3. The contact lens product of claim 2, wherein theweight percentage concentration of the cycloplegic agent in the buffersolution is ConA, and the following condition is satisfied:0.01%≤ConA≤0.1%.
 4. The contact lens product of claim 3, wherein theweight percentage concentration of the cycloplegic agent in the buffersolution is ConA, and the following condition is satisfied:0.01%≤ConA≤0.05%.
 5. The contact lens product of claim 1, wherein acomposition for manufacturing the multifocal contact lens comprises ablue-light blocking agent.
 6. The contact lens product of claim 5,wherein the blue-light blocking agent is 4-(phenyldiazenyl) phenylmethacrylate.
 7. The contact lens product of claim 1, wherein acomposition for manufacturing the multifocal contact lens comprises a UV(Ultraviolet) blocking agent.
 8. The contact lens product of claim 7,wherein the UV blocking agent is2-(2′-hydroxy-5′-methacryloxyethylphenyl)-2H-benzotriazole or2-(4-benzoyl-3-hydroxyphenoxy)ethyl acrylate.
 9. The contact lensproduct of claim 1, wherein the multifocal contact lens is made ofsilicone hydrogel.
 10. The contact lens product of claim 9, wherein acomposition for manufacturing the silicone hydrogel comprises2-hydroxyethyl methacrylate,3-methacryloyloxypropyltris(trimethylsilyloxy)silane,2-hydroxy-2-methyl-propiophenone, N-vinyl-2-pyrrolidinone, N,N-dimethylacrylamide, ethylene glycol dimethacrylate,3-(3-methacryloxy-2-hydroxypropoxy)propylbis(trimethylsiloxy)methylsilane,isopropyl alcohol and methacrylic acid.
 11. The contact lens product ofclaim 9, wherein a composition for manufacturing the silicone hydrogelcomprises 2-hydroxyethyl methacrylate,3-methacryloyloxypropyltris(trimethylsilyloxy)silane,2-hydroxy-2-methyl-propiophenone, N-vinyl-2-pyrrolidinone, N,N-dimethylacrylamide, ethylene glycol dimethacrylate,(3-acryloxy-2-hydroxypropoxypropyl)terminated polydimethylsiloxane and1-hexanol.
 12. The contact lens product of claim 9, wherein acomposition for manufacturing the silicone hydrogel comprises2-hydroxyethyl methacrylate,3-methacryloyloxypropyltris(trimethylsilyloxy)silane,2-hydroxy-2-methyl-propiophenone, N-vinyl-2-pyrrolidinone, N,N-dimethylacrylamide, polysiloxane macromer, methyl methacrylate and ethanol. 13.The contact lens product of claim 1, wherein the multifocal contact lensis made of hydrogel.
 14. The contact lens product of claim 13, wherein acomposition for manufacturing the hydrogel comprises 2-hydroxyethylmethacrylate, ethylene glycol dimethacrylate,2-hydroxy-2-methyl-propiophenone, glycerol, 1,1,1-trimethylol propanetrimethacrylate and methacrylic acid.
 15. The contact lens product ofclaim 13, wherein a composition for manufacturing the hydrogel comprises2-hydroxyethyl methacrylate, ethylene glycol dimethacrylate,2-hydroxy-2-methyl-propiophenone, glycerol, 1,1,1-trimethylol propanetrimethacrylate and glycerol monomethacrylate.
 16. The contact lensproduct of claim 13, wherein a composition for manufacturing thehydrogel comprises 2-hydroxyethyl methacrylate, ethylene glycoldimethacrylate, 2-hydroxy-2-methyl-propiophenone, glycerol andN-vinyl-2-pyrrolidinone.
 17. The contact lens product of claim 1,wherein a number of the annular regions is two, the annular regions area first annular region and a second annular region, the central region,the second annular region and the first annular region are sequentiallyconnected from a center of the multifocal contact lens to a periphery ofthe multifocal contact lens and are concentric, a diopter of the secondannular region is different from the diopter of the central region, andat least one of the central region, the second annular region and thefirst annular region is aspheric.
 18. The contact lens product of claim17, wherein the diameter of the central region of the multifocal contactlens is DiC, and the following condition is satisfied:4 mm<DiC≤10 mm.
 19. The contact lens product of claim 17, wherein anouter diameter of the first annular region of the multifocal contactlens is DiP1, and the following condition is satisfied:6 mm≤DiP1 ≤17 mm.
 20. The contact lens product of claim 17, wherein anouter diameter of the second annular region of the multifocal contactlens is DiP2, and the following condition is satisfied:5 mm≤DiP2≤13 mm.
 21. The contact lens product of claim 17, wherein thediameter of the central region of the multifocal contact lens is DiC, anouter diameter of the first annular region of the multifocal contactlens is DiP1, and the following condition is satisfied:0.15≤DiC/DiP1 <1.
 22. The contact lens product of claim 17, wherein thediameter of the central region of the multifocal contact lens is DiC, anouter diameter of the second annular region of the multifocal contactlens is DiP2, and the following condition is satisfied:0.2≤DiC/DiP2<1.
 23. The contact lens product of claim 17, wherein thediopter of the central region of the multifocal contact lens is PowC,the maximum diopter of the first annular region of the multifocalcontact lens is PowP1, and the following condition is satisfied:0.75 D≤|PowC−PowP1|<12 D.